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Article

The methylation profiles of PRDM promoters in non–small cell lung cancer

1 May 2018

Abstract excerpt

Background: Non–small cell lung cancer (NSCLC) is one of the leading malignant tumors worldwide. Aberrant gene promoter methylation contributes to NSCLC, and PRDM is a tumor suppressor gene family that possesses histone methyltransferase activity. This study aimed to investigate whether aberrant methylation of PRDM promoter is involved in NSCLC. Materials and methods: Primary tumor tissues, adjacent nontumorous...

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Share to Epigenetics and DNA Methylation
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 29872311
DOI: 10.2147/ott.s156775

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