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Article

The effect of point mutations in dihydrofolate reductase genes and multidrug resistance gene 1-86 on treatment of falciparum malaria in Sudan.

Journal of infection in developing countries - 8 Mar 2010

Yusuf Rahma Udu, Omar Sabah Ahmed, Ngure Raphael Muchangi

Abstract excerpt

BACKGROUND: One of the major problems to the treatment of malaria is the emergence and spread of parasite resistant to antimalarial drugs. Due to increased chloroquine (CQ) resistance, the antifolate combinations are becoming important in the chemotherapy of falciparum malaria. However, resistance to antifolate exists and they are still effective in the above combinations. This study aimed at determining the...

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Source

Identifiers

PMID: 20212335
DOI: 10.3855/jidc.630

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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