Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evolution of Plasmodium falciparum drug resistance genes following artemisinin combination therapy in Sudan

1 Jun 2019

Abstract excerpt

BACKGROUND: Malaria control efforts in Sudan rely heavily on case management. In 2004, health authorities adopted artemisinin-based combination therapies (ACTs) for the treatment of uncomplicated malaria. However, some recent surveys have reported ACT failure and a prevalent irrational malaria treatment practice. Here we examine whether the widespread use of ACT and failure to adhere to national guidelines have...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Calpain Protease Function and Regulation
Share to Malaria Research and Control
Share to Pharmaceutical Quality and Counterfeiting

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31369106
DOI: 10.1093/trstmh/trz059

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evolution of Plasmodium falciparum drug resistance genes following artemisinin combination therapy in SudanPMID 31369106Read ↗

Antimalarial drug resistance molecular makers of Plasmodium falciparum isolates from Sudan during 2015-2017.Semantic proximity Read ↗

Historical literature review and molecular analysis of malaria drug resistance markers of Plasmodium falciparum field-isolates from Sudan.Semantic proximity Read ↗

Selection of pfdhfr/pfdhps alleles and declining artesunate/sulphadoxine-pyrimethamine efficacy against Plasmodium falciparum eight years after deployment in eastern SudanSemantic proximity Read ↗

Frequency distribution of antimalarial drug resistance alleles among Plasmodium falciparum isolates from Gezira State, central Sudan, and Gedarif State, eastern Sudan.Semantic proximity Read ↗

Prevalence of mutations in the antifolates resistance-associated genes (dhfr and dhps) in Plasmodium vivax parasites from Eastern and Central Sudan.Semantic proximity Read ↗

High efficacy of artemether-lumefantrine and declining efficacy of artesunate + sulfadoxine-pyrimethamine against Plasmodium falciparum in Sudan (2010-2015): evidence from in vivo and molecular marker studies.Semantic proximity Read ↗

Evolution of drug-resistance genes in Plasmodium falciparum in an area of seasonal malaria transmission in Eastern Sudan.Semantic proximity Read ↗

High Prevalence of Artemisinin-Resistant Plasmodium falciparum, Southeastern SudanSemantic proximity Read ↗

Plasmodium falciparum population structure in Sudan post artemisinin-based combination therapy.Semantic proximity Read ↗

Falciparum malaria molecular drug resistance in the Democratic Republic of Congo: a systematic review.Semantic proximity Read ↗

Absence of kelch13 artemisinin resistance markers but strong selection for lumefantrine-tolerance molecular markers following 18 years of artemisinin-based combination therapy use in Mpumalanga Province, South Africa (2001–2018)Semantic proximity Read ↗

Absence of Plasmodium falciparum artemisinin resistance gene mutations eleven years after the adoption of artemisinin-based combination therapy in Nigeria.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.