Article
High efficacy of artemether-lumefantrine and declining efficacy of artesunate + sulfadoxine-pyrimethamine against Plasmodium falciparum in Sudan (2010-2015): evidence from in vivo and molecular marker studies.
Malaria journal - 21 May 2016
Adeel Ahmed A, Elnour Fahad Awad Ali, Elmardi Khalid Abdalmutalab, Abd-Elmajid Mona B, Elhelo Mai Mahmoud, Ali Mousab S, Adam Mariam A, Atta Hoda, Zamani Ghasem, Warsame Marian, Barrette Amy, Mohammady Hanan El, Nada Rania A
Abstract excerpt
BACKGROUND: The present paper reports on studies that evaluated artesunate + sulfadoxine-pyrimethamine (AS + SP) which is the first-line drug and artemether-lumefantrine (AL) which is a second-line drug against uncomplicated falciparum malaria in Sudan. This evaluation was performed in twenty studies covering six sentinel sites during five successive annual malaria transmission seasons from 2010 to 2015. METHODS:...
Topics
- Adolescent
- Adult
- Aged
- Aged, 80 and over
- Antimalarials
- Artemether, Lumefantrine Drug Combination
- Artemisinins
- Artesunate
- Child