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Article

Neuroprotective effects of the drug GVT (monosodium luminol) are mediated by the stabilization of Nrf2 in astrocytes.

Neurochemistry international - 1 Jan 2000

Reddy Pichili Vijaya Bhaskar, Lungu Gina, Kuang Xianghong, Stoica George, Wong Paul K Y

Abstract excerpt

Oxidative stress is implicated in various kinds of neurological disorders, including human immunodeficiency virus (HIV) associated dementia (HAD). Our laboratory has been studying the murine retrovirus ts1, a pathogenic mutant of the Moloney murine leukemia virus (MoMuLV), as a model for HAD. Like HIV in humans, ts1 induces oxidative stress and progressive neurodegeneration in mice. We have shown previously that...

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Identifiers

PMID: 20211212
DOI: 10.1016/j.neuint.2010.02.017
PMCID: PMC4109344

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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