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Article

Human TRIB2 is a repressor of FOXO that contributes to the malignant phenotype of melanoma cells.

Oncogene - 20 May 2010

Zanella F, Renner O, García B, Callejas S, Dopazo A, Peregrina S, Carnero A, Link W

Abstract excerpt

FOXO transcription factors are evolutionarily conserved proteins that orchestrate gene expression programs known to control a variety of cellular processes such as cell cycle, apoptosis, DNA repair and protection from oxidative stress. As the abrogation of FOXO function is a key feature of many tumor cells, regulation of FOXO factors is receiving increasing attention in cancer research. In order to discover genes...

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Identifiers

PMID: 20208562
DOI: 10.1038/onc.2010.58

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TRIB2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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