BDNF mRNA expression of peripheral blood mononuclear cells was decreased in depressive patients who had or had not recently attempted suicide.

Abstract excerpt

BACKGROUND: Recent reports have suggested a pathophysiological role for brain-derived neurotrophic factor (BDNF) in major depression and suicide. We evaluate BDNF mRNA in peripheral blood mononuclear cells (PBMCs) of patients with major depression who had or had not recently attempted suicide. METHODS: BDNF mRNA expression was examined in PBMCs of 30 major depressed patients without recent suicide attempts, 30...

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