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Article

Distinct hematopoietic stem cell subtypes are differentially regulated by TGF-beta1.

Cell stem cell - 5 Mar 2010

Challen Grant A, Boles Nathan C, Chambers Stuart M, Goodell Margaret A

Abstract excerpt

The traditional view of hematopoiesis has been that all the cells of the peripheral blood are the progeny of a unitary homogeneous pool of hematopoietic stem cells (HSCs). Recent evidence suggests that the hematopoietic system is actually maintained by a consortium of HSC subtypes with distinct functional characteristics. We show here that myeloid-biased HSCs (My-HSCs) and lymphoid-biased HSCs (Ly-HSCs) can be...

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Identifiers

PMID: 20207229
DOI: 10.1016/j.stem.2010.02.002
PMCID: PMC2837284

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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