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REVIEW PAPER: Animals as Models of Age-Related Macular Degeneration

9 Apr 2010

Abstract excerpt

Age-related macular degeneration (AMD) is a degenerative condition that begins in Bruch's membrane and progresses to involve the retinal pigment epithelium and ultimately the overlying photoreceptors. The only required etiologic factor is age, and AMD is regarded as the leading cause of blindness in individuals older than 65 years. AMD results from variable contributions of age, environment, and genetic...

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PMID: 20382825
DOI: 10.1177/0300985809359598

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