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Article

Analysis of common germline polymorphisms as prognostic factors in patients with lymph node-positive breast cancer.

Journal of cancer research and clinical oncology - 1 Dec 2010

Knechtel Gudrun, Hofmann Günter, Gerger Armin, Renner Wilfried, Langsenlehner Tanja, Szkandera Joanna, Wolf Gerald, Samonigg Hellmut, Krippl Peter, Langsenlehner Uwe

Abstract excerpt

PURPOSE: Women with breast cancer that initially involves local lymph nodes have a higher risk for local recurrence or developing metastases. Recent data suggest that germline polymorphism is a significant, previously unrecognized factor in breast cancer progression and metastasis. We assessed the influence of 16 selected common germline polymorphisms in disease-free survival and overall survival among 216 women...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20204402
DOI: 10.1007/s00432-010-0839-2

Genes

FAS
ITGA2
CCND1
FASLG
ITGB3
MMP1
MMP3
MTHFR
PTGS2
TGFB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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