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Trophoblast Fusion in Hypertensive Disorders of Pregnancy and Preeclampsia

21 Mar 2025

Abstract excerpt

Trophoblast fusion into the multinucleated syncytiotrophoblast (SCT) appears as an inescapable feature of placentation in mammals and other viviparous species. The trophoblast cells underlying the syncytium are considered a reservoir for the restoration of the aging peripheric structure. The transition from trophoblasts to SCTs has to be tightly regulated, and could be altered by genetic anomalies or...

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PMID: 40243430
DOI: 10.3390/ijms26072859

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