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Article

Association analysis of single nucleotide polymorphisms at five loci: comparison between atopic dermatitis and asthma in the Chinese Han population.

PloS one - 1 Jan 2012

Tang Hua-Yang, Tang Xian-Fa, Zuo Xian-Bo, Gao Jin-Ping, Sheng Yu-Jun, Li Yang, Zhou Fu-Sheng, Yin Xian-Yong, Xiao Feng-Li, Du Wei-Dong, Yang Sen, Sun Liang-Dan, Zhang Xue-Jun

Abstract excerpt

Atopic diseases, such as atopic dermatitis (AD) and asthma, are closely related to clinical phenotypes with hypersensitivity, and often share some similar genetic and pathogenic bases. Our recent GWAS identified three susceptibility gene/loci FLG (rs11204971 and rs3126085), 5q22.1 (rs10067777, rs7701890, rs13360927 and ) and 20q13.33 () to AD. The effect of these AD associated polymorphisms in...

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Identifiers

PMID: 22545103
DOI: 10.1371/journal.pone.0035334
PMCID: PMC3335873

Genes

FLG

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