Article
Imatinib mesylate in patients with WHO B3 thymomas and thymic carcinomas.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Oct 2009
Giaccone Giuseppe, Rajan Arun, Ruijter Rita, Smit Egbert, van Groeningen Cees, Hogendoorn Pancras C W
Abstract excerpt
Thymic malignancies are rare tumors of the mediastinum. c-KIT is highly expressed in thymic carcinomas (TC) but infrequently in thymomas. Anecdotal experience suggests activity of imatinib mesylate in TC. Patients with unresectable World Health Organization B3 thymomas or TC, performance status 0...
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