Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hemochromatosis gene and nonalcoholic fatty liver disease: a systematic review and meta-analysis.

Journal of hepatology - 1 Nov 2011

Hernaez Ruben, Yeung Edwina, Clark Jeanne M, Kowdley Kris V, Brancati Frederick L, Kao Wen Hong Linda

Abstract excerpt

BACKGROUND & AIMS: Previous studies examining the relationship between the C282Y and H63D HFE mutations and presence of nonalcoholic fatty liver disease (NAFLD) have yielded conflicting results. The goal of this study was to systematically evaluate and summarize data on the association between these two variants and the presence of NAFLD. METHODS: The authors searched EMBASE and PUBMED from August 1, 1996 to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Fatty Liver
Share to Genotype
Share to Hemochromatosis Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Histocompatibility Antigens Class I

Share to Membrane Proteins

Share to Mutation

Share to Non-alcoholic Fatty Liver Disease

Share to White People

Source

Open in PubMed Open full text

Identifiers

PMID: 21354231
DOI: 10.1016/j.jhep.2011.02.013
PMCID: PMC3611963

Genes

HFE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hemochromatosis gene and nonalcoholic fatty liver disease: a systematic review and meta-analysis.PMID 21354231Read ↗

HFE genetic variability and risk of alcoholic liver disease: A meta-analysis.Semantic proximity Read ↗

Association of HFE gene mutations with nonalcoholic fatty liver disease in the Iranian population.Semantic proximity Read ↗

An epidemiologic study on the incidence and significance of HFE mutations in a Korean cohort with nonalcoholic fatty liver disease.Semantic proximity Read ↗

Nonalcoholic fatty liver disease and HFE gene mutations: a Polish study.Semantic proximity Read ↗

Heterozygosity for the hemochromatosis gene in liver diseases--prevalence and effects on liver histology.Semantic proximity Read ↗

HFE genotype in patients with hemochromatosis and other liver diseases.Semantic proximity Read ↗

HFE mutations, hepatic iron, and fibrosis: ethnic-specific association of NASH with C282Y but not with fibrotic severity.Semantic proximity Read ↗

Association between C282Y and H63D mutations of the HFE gene with hepatocellular carcinoma in European populations: a meta-analysis.Semantic proximity Read ↗

HFE genotype, parenchymal iron accumulation, and liver fibrosis in patients with nonalcoholic fatty liver disease.Semantic proximity Read ↗

The HFE gene heterozygosis H63D: a cofactor for liver damage in patients with steatohepatitis? Epidemiological and clinical considerations.Semantic proximity Read ↗

HFE gene mutations in patients with alcoholic liver disease. A prospective study from northwestern Poland.Semantic proximity Read ↗

Association of Hemochromatosis HFE p.C282Y Homozygosity With Hepatic Malignancy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.