Article
Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium: Design of prospective meta-analyses of genome-wide association studies from 5 cohorts.
Circulation. Cardiovascular genetics - 1 Feb 2009
Psaty Bruce M, O'Donnell Christopher J, Gudnason Vilmundur, Lunetta Kathryn L, Folsom Aaron R, Rotter Jerome I, Uitterlinden André G, Harris Tamara B, Witteman Jacqueline C M, Boerwinkle Eric
Abstract excerpt
BACKGROUND: The primary aim of genome-wide association studies is to identify novel genetic loci associated with interindividual variation in the levels of risk factors, the degree of subclinical disease, or the risk of clinical disease. The requirement for large sample sizes and the importance o...
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