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EDA Variants Are Responsible for Approximately 90% of Deciduous Tooth Agenesis.

International journal of molecular sciences - 27 Sept 2024

Su Lanxin, Lin Bichen, Yu Miao, Liu Yang, Sun Shichen, Feng Hailan, Liu Haochen, Han Dong

Abstract excerpt

Deciduous tooth agenesis is a severe craniofacial developmental defect because it affects masticatory function from infancy and may result in delayed growth and development. Here, we aimed to identify the crucial pathogenic genes and clinical features of patients with deciduous tooth agenesis. We recruited 84 patients with severe deciduous tooth agenesis. Whole-exome and Sanger sequencing were used to identify...

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Anodontia
Bone Morphogenetic Protein 4
Ectodysplasins
Homeobox Protein PITX2
Low Density Lipoprotein Receptor-Related Protein-6

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Tooth, Deciduous

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PMID: 39408781
DOI: 10.3390/ijms251910451
PMCID: PMC11477375

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