Article
Flagellin-induced corneal antimicrobial peptide production and wound repair involve a novel NF-kappaB-independent and EGFR-dependent pathway.
PloS one - 26 Feb 2010
Gao Nan, Kumar Ashok, Jyot Jeevan, Yu Fu-Shin
Abstract excerpt
BACKGROUND: The bacterial protein flagellin plays a major role in stimulating mucosal surface innate immune response to bacterial infection and uniquely induces profound cytoprotection against pathogens, chemicals, and radiation. This study sought to determine signaling pathways responsible for t...
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