The<i>Brucella abortus</i>Phosphoglycerate Kinase Mutant Is Highly Attenuated and Induces Protection Superior to That of Vaccine Strain 19 in Immunocompromised and Immunocompetent Mice

Abstract excerpt

Brucella abortus is a facultative intracellular bacterial pathogen that causes abortion in domestic animals and undulant fever in humans. The mechanism of virulence of Brucella spp. is not yet fully understood. Therefore, it is crucial to identify new molecules that can function as virulence factors to better understand the host-pathogen interplay. Herein, we identified the gene encoding the phosphoglycerate...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Brucella: diagnosis, epidemiology, treatment
• Share to Burkholderia infections and melioidosis