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Article

Fitness epistasis among 6 biosynthetic loci in the budding yeast Saccharomyces cerevisiae.

The Journal of heredity - 1 Jan 2000

Hall David W, Agan Matthew, Pope Sara C

Abstract excerpt

We generated all possible haploid and homozygous diploid genotypes at 6 biosynthetic loci in yeast and scored their fitness to examine whether there was any pattern of weak synergistic epistasis, which is a requirement of the deterministic mutation model for the evolution of sex. We measured 4 components of fitness: haploid growth rate, haploid mating efficiency, diploid growth rate, and diploid sporulation...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20194517
DOI: 10.1093/jhered/esq007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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