Article
Factors affecting the genetic load in Drosophila: synergistic epistasis and correlations among fitness components.
Evolution; international journal of organic evolution - 1 Oct 2000
Whitlock M C, Bourguet D
Abstract excerpt
Two factors that can affect genetic load, synergistic epistasis and sexual selection, were investigated in Drosophila melanogaster. A set of five chromosomal regions containing visible recessive mutations were put together in all combinations to create a full set of 32 homozygous lines fixed for different numbers of known mutations. Two measures of fitness were made for each line: productivity (a combined measure...
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