Article
Mutations of NFKBIA in biopsy specimens from Hodgkin lymphoma.
Cancer genetics and cytogenetics - 1 Mar 2010
Liu Xiaojian, Yu Hong, Yang Wentao, Zhou Xiaoyan, Lu Hongfeng, Shi Daren
Abstract excerpt
To determine the possible alteration of the inhibitor kappaBalpha (HUGO-approved symbol, NFKBIA) gene in Chinese Hodgkin lymphoma (HL) patients, NFKBIA mRNA and protein expression in 22 primary HL patients were examined. Individual tumor cells were used for amplification to obtain the NFKBIA gene, and the polymerase chain reaction products were sequenced. Compared with reactive surrounding lymphocytes, inhibitor...
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