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Antibodies to citrullinated proteins: molecular interactions and arthritogenicity

23 Dec 2009

Abstract excerpt

The discovery of antibodies specific for citrullinated protein epitopes [anti-citrullinated protein antibodies (ACPAs)] is a hallmark for the diagnosis and prognosis of rheumatoid arthritis (RA) and will also be a useful tool for understanding the fundamental pathologic processes. There are several essential questions pertaining to ACPA that remain to be explored, such as understanding the early specificity of...

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PMID: 20192990
DOI: 10.1111/j.0105-2896.2009.00853.x

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