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Article

Neurotoxicity screening in a multipotent neural stem cell line established from the mouse brain.

Journal of Korean medical science - 1 Mar 2010

Choi Yong-Soo, Lee Min-Cheol, Kim Hyung-Seok, Lee Kyung-Hwa, Park Yeoung-Geol, Kim Hyun-Kyung, Jeong Han-Seong, Kim Myeong-Kyu, Woo Young-Jong, Kim Seung-Up, Ryu Jae-Kyu, Choi Hyun-Beom

Abstract excerpt

Neural stem cells (NSCs) have mainly been applied to neurodegeneration in some medically intractable neurologic diseases. In this study, we established a novel NSC line and investigated the cytotoxic responses of NSCs to exogenous neurotoxicants, glutamates and reactive oxygen species (ROS). A multipotent NSC line, B2A1 cells, was established from long-term primary cultures of oligodendrocyte-enriched cells from...

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Identifiers

PMID: 20191045
DOI: 10.3346/jkms.2010.25.3.440
PMCID: PMC2826742

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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