Article
Effects of salvianolic acid B on survival, self-renewal and neuronal differentiation of bone marrow derived neural stem cells.
European journal of pharmacology - 15 Dec 2012
Zhang Nan, Kang Tingguo, Xia Yang, Wen Qingping, Zhang Xiaodan, Li Hongyan, Hu Yv, Hao Haiguang, Zhao Dan, Sun Dong, Yan Yaping, Zhang Guang-Xian, Yang Jingxian
Abstract excerpt
Our previous study has demonstrated the therapeutic potential of bone marrow derived-neural stem cells (BM-NSCs) in CNS disorders; however, the beneficial effects are modest due to the poor survival and low neural differentiation frequency. Here, we demonstrate that salvianolic acid B (Sal B), a potent aqueous of a well known Chinese medicine herb, Salvia miltiorrhiza, possesses the ability to promote BM-NSCs...
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