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A stress-induced cellular aging model with postnatal neural stem cells

13 Mar 2014

Abstract excerpt

Aging refers to the physical and functional decline of the tissues over time that often leads to age-related degenerative diseases. Accumulating evidence implicates that the senescence of neural stem cells (NSCs) is of paramount importance to the aging of central neural system (CNS). However, exploration of the underlying molecular mechanisms has been hindered by the lack of proper aging models to allow the...

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PMID: 24625975
DOI: 10.1038/cddis.2014.82

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