Article

Investigation of Oxidative Stress and Mitochondrial Damage on Rat Derived Neural Stem Cells in 3D Organoid Models

2024-09-03

Abstract excerpt

<title>Abstract</title> <p>Our goal was to investigate mitochondrial damage in a three-dimensional (3D) neural stem cell (NSC) organoid model using oxidative stress-induced NSCs as primary research method. To create an in vitro organoid model, we utilized NSCs that were exposed to oxidative stress by treating them with hydrogen peroxide (H<sub>2</sub>O<sub>2</sub>) at a concentration of 75 µM, leading to mitochon...

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Literature Corpus work: 026e2588-f07e-58e5-8689-90a66a353a3c
DOI: 10.21203/rs.3.rs-4873168/v1

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