Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The H63D genetic variant of the HFE gene is independently associated with the virological response to interferon and ribavirin therapy in chronic hepatitis C.

European journal of gastroenterology & hepatology - 1 Oct 2010

Carneiro Marcos V, Souza Fernanda F, Teixeira Andreza C, Figueiredo José F C, Villanova Marcia G, Secaf Marie, Passos Afonso D C, Ramalho Leandra N Z, Carneiro Fabiana P, Zucoloto Sérgio, Candolo Martinelli Ana L

Abstract excerpt

BACKGROUND: Conflicting results have been reported in studies evaluating the relationship between serum markers of iron overload, liver iron deposits, and HFE mutations (C282Y and H63D) in chronic hepatitis C patients, and also their impact on the response to therapy in these patients. AIM: To evaluate the role of HFE mutations in the severity of liver disease and in the response to therapy in chronic hepatitis...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drug Resistance, Viral
Share to Hemochromatosis Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hepatitis C, Chronic

Share to Histocompatibility Antigens Class I

Share to Interferon-alpha

Share to Interferon alpha-2

Share to Ribavirin

Source

Identifiers

PMID: 20555268
DOI: 10.1097/MEG.0b013e32833bec1e

Genes

HFE

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The H63D genetic variant of the HFE gene is independently associated with the virological response to interferon and ribavirin therapy in chronic hepatitis C.PMID 20555268Read ↗

HFE mutations and chronic hepatitis C: H63D and C282Y heterozygosity are independent risk factors for liver fibrosis and cirrhosis.Semantic proximity Read ↗

Roles of iron and HFE mutations on severity and response to therapy during retreatment of advanced chronic hepatitis C.Semantic proximity Read ↗

The effect of HFE gene mutation and iron overload on sustained virological response in Egyptian chronic hepatitis C patients treated with daclatasvir and sofosbuvir.Semantic proximity Read ↗

Effect of HFE gene polymorphism on sustained virological response in patients with chronic hepatitis C and elevated serum ferritin.Semantic proximity Read ↗

[HFE gene mutations, hepatic iron content, and histological severity in hepatitis C virus-induced chronic hepatitis].Semantic proximity Read ↗

The role of iron overload and HFE gene mutations in the era of pegylated interferon and ribavirin treatment of chronic hepatitis C.Semantic proximity Read ↗

Influence of HFE gene polymorphism on the progression and treatment of chronic hepatitis C.Semantic proximity Read ↗

Clinical impact of HFE mutations in Japanese patients with chronic hepatitis C.Semantic proximity Read ↗

Hepatitis C, iron status, and disease severity: relationship with HFE mutations.Semantic proximity Read ↗

Raised serum ferritin predicts non-response to interferon and ribavirin treatment in patients with chronic hepatitis C infection.Semantic proximity Read ↗

The role of iron and haemochromatosis gene mutations in the progression of liver disease in chronic hepatitis C.Semantic proximity Read ↗

Hepatic iron overload in patients with chronic viral hepatitis: role of HFE gene mutations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.