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Mechanisms of Defense against Intracellular Pathogens Mediated by Human Macrophages

6 May 2016

Abstract excerpt

The key question our work has sought to address has been, "What are the necessary and sufficient conditions that engender protection from intracellular pathogens in the human host?" The origins of this work derive from a long-standing interest in the mechanisms of protection against two such paradigmatic intracellular pathogens, Mycobacterium tuberculosis and Mycobacterium leprae, that have brilliantly adapted to...

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PMID: 27337485
DOI: 10.1128/microbiolspec.mchd-0006-2015

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