Article
Identification of the most active interleukin-32 isoform.
Immunology - 1 Apr 2009
Choi Ji-Da, Bae Su-Young, Hong Jae-Woo, Azam Tania, Dinarello Charles A, Her Erk, Choi Whan-Soo, Kim Bo-Kyung, Lee Chang-Kwon, Yoon Do-Young, Kim Sun-Jong, Kim Soo-Hyun
Abstract excerpt
Cytokines are crucial in host defence against pathogens such as bacteria, viruses, fungi and parasites. A newly described cytokine, interleukin-32 (IL-32), induces various proinflammatory cytokines (tumour necrosis factor-alpha, IL-1beta, IL-6) and chemokines in both human and mouse cells through the nuclear factor-kappaB and p38 mitogen-activated protein kinase inflammatory signal pathway. The IL-32 primarily...
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