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Article

Variable proton-pumping stoichiometry in structural variants of cytochrome c oxidase.

Biochimica et biophysica acta - 1 Jan 2000

Brzezinski Peter, Johansson Ann-Louise

Abstract excerpt

Cytochrome c oxidase is a multisubunit membrane-bound enzyme, which catalyzes oxidation of four molecules of cytochrome c2+ and reduction of molecular oxygen to water. The electrons are taken from one side of the membrane while the protons are taken from the other side. This topographical arrangement results in a charge separation that is equivalent to moving one positive charge across the membrane for each...

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Identifiers

PMID: 20184858
DOI: 10.1016/j.bbabio.2010.02.020

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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