Article
Critical role of natural killer cells in the rejection of human hepatocytes after xenotransplantation into immunodeficient mice.
Transplant international : official journal of the European Society for Organ Transplantation - 1 Sept 2010
Kawahara Toshiyasu, Douglas Donna N, Lewis Jamie, Lund Garry, Addison William, Tyrrell David Lorne, Churchill Thomas A, Kneteman Norman M
Abstract excerpt
The severe combined immunodeficiency/albumin linked-urokinase type plasminogen activator (SCID/Alb-uPA) human liver chimeric mouse model has added a new dimension to studies of liver based human diseases and has important potential for study of human hepatic drug metabolism. However, it remains u...
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