Article
Evidence for interaction between 5-hydroxytryptamine (serotonin) receptor 2A and MHC type II molecules in the development of rheumatoid arthritis.
European journal of human genetics : EJHG - 1 Jul 2010
Seddighzadeh Maria, Korotkova Marina, Källberg Henrik, Ding Bo, Daha Nina, Kurreeman Fina A S, Toes Rene E M, Huizinga Tom W, Catrina Anca I, Alfredsson Lars, Klareskog Lars, Padyukov Leonid
Abstract excerpt
It has repeatedly been suggested that the development of complex diseases can be elucidated by gene-gene interactions. Recently, we found that HTR2A, a member of the serotonin receptor family, is associated with rheumatoid arthritis (RA). This study was aimed to investigate the possibility of a g...
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