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Article

Genome-wide association study for femoral neck bone geometry

13 Jul 2009

Abstract excerpt

Poor femoral neck bone geometry at the femur is an important risk factor for hip fracture. We conducted a genome-wide association study (GWAS) of femoral neck bone geometry, examining approximately 379,000 eligible single-nucleotide polymorphisms (SNPs) in 1000 Caucasians. A common genetic variant, rs7430431 in the receptor transporting protein 3 (RTP3) gene, was identified in strong association with the buckling...

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PMID: 20175129
DOI: 10.1359/jbmr.090726

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