Article
Identification and characterization of tumorigenic liver cancer stem/progenitor cells.
Gastroenterology - 1 Jun 2007
Ma Stephanie, Chan Kwok-Wah, Hu Liang, Lee Terence Kin-Wah, Wo Jana Yim-Hung, Ng Irene Oi-Lin, Zheng Bo-Jian, Guan Xin-Yuan
Abstract excerpt
BACKGROUND & AIMS: Recent efforts in stem cell biology suggest that tumors are organized in a hierarchy of heterogeneous cell populations and that the capability to maintain tumor formation/growth specifically resides in a small population of cells called cancer stem cells (CSCs). The aim of this study is to identify, isolate, and characterize the CSC population that drives and maintains hepatocellular carcinoma...
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