Article
A critical assessment of comparative molecular modeling of tertiary structures of proteins.
Proteins - 1 Nov 1995
Mosimann S, Meleshko R, James M N
Abstract excerpt
In spite of the tremendous increase in the rate at which protein structures are being determined, there is still an enormous gap between the numbers of known DNA-derived sequences and the numbers of three-dimensional structures. In order to shed light on the biological functions of the molecules, researchers often resort to comparative molecular modeling. Earlier work has shown that when the sequence alignment is...
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