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Article

Evidence for molecular differences in prostate cancer between African American and Caucasian men.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Sept 2014

Khani Francesca, Mosquera Juan Miguel, Park Kyung, Blattner Mirjam, O'Reilly Catherine, MacDonald Theresa Y, Chen Zhengming, Srivastava Abhishek, Tewari Ashutosh K, Barbieri Christopher E, Rubin Mark A, Robinson Brian D

Abstract excerpt

PURPOSE: The aim of this study was to compare the frequency of ERG rearrangement, PTEN deletion, SPINK1 overexpression, and SPOP mutation in prostate cancer in African American and Caucasian men. EXPERIMENTAL DESIGN: Dominant tumor nodules from radical prostatectomy specimens of 105 African American men (AAM) were compared with 113 dominant nodules from Caucasian men (CaM). Clinical and pathologic characteristics...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25056375
DOI: 10.1158/1078-0432.CCR-13-2265
PMCID: PMC4167562

Genes

ERG
PTEN
SPINK1
SPOP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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