Mitochondrial protein import: isolation and characterization of the Saccharomyces cerevisiae MFT1 gene.

doi:10.1007/BF00261691

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Article

Mitochondrial protein import: isolation and characterization of the Saccharomyces cerevisiae MFT1 gene.

Molecular & general genetics : MGG - 1 Mar 1991

Garrett J M, Singh K K, Vonder Haar R A, Emr S D

Abstract excerpt

Mitochondrial targeting of an Atp2-LacZ fusion protein confers a respiration-defective phenotype on yeast cells. This effect has been utilized to select strains that grow on nonfermentable carbon sources, some of which have decreased levels of hybrid protein localized to the organelle. Many of the mutants obtained were also temperature-sensitive for growth on all media. The recessive mft (mitochondrial fusion...

Topics

Amino Acid Sequence
Base Sequence
Cloning, Molecular
DNA, Fungal
DNA-Binding Proteins
Ethyl Methanesulfonate
Fungal Proteins
Genes, Fungal
Genetic Complementation Test
Mitochondria
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Open Reading Frames

Oxygen Consumption

Phenotype

Recombinant Fusion Proteins

Restriction Mapping

Saccharomyces cerevisiae

Source

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Identifiers

PMID: 2017143
DOI: 10.1007/BF00261691

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2017143-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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