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Article

Influence of serotonin 3A and 3B receptor genes on clozapine treatment response in schizophrenia.

Pharmacogenetics and genomics - 1 Apr 2010

Souza Renan P, de Luca Vincenzo, Meltzer Herbert Y, Lieberman Jeffrey A, Kennedy James L

Abstract excerpt

Earlier results suggest a minor role of variants in the serotonin 3 receptor (HTR3) subunit genes on antipsychotic treatment outcome of schizophrenia patients. In this study, we further investigated the role of the subunits A and B of the HTR3 receptor using 140 schizophrenia patients taking clozapine for 6 months. We have found significant allelic association of clozapine response with three variants in the...

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Source

Identifiers

PMID: 20168265
DOI: 10.1097/FPC.0b013e328337ce3e

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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