Article
Novel locus for fibrinogen in 3' region of LEPR gene in island population of Vis (Croatia).
Journal of human genetics - 1 Nov 2014
Tomas Željka, Petranović Matea Zajc, Škarić-Jurić Tatjana, Barešić Ana, Salihović Marijana Peričić, Narančić Nina Smolej
Abstract excerpt
Leptin, a possible mediator between energy homeostasis, inflammation and cardiovascular disease (CVD), acts via leptin receptors. We investigated association of single-nucleotide polymorphisms (SNPs) and haplotypes of the leptin receptor gene (LEPR) with several CVD risk factors: body mass index, waist circumference (WC), serum lipids, fibrinogen and C-reactive protein levels. Thirty-one SNPs in and near LEPR...
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