Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Differences in the photogenotoxic potential of two fluoroquinolones as shown in diploid yeast strain (Saccharomyces cerevisae) and supercoiled plasmid DNA.

Mutation research - 22 Jun 2000

Marrot L, Agapakis-Causse C

Abstract excerpt

Fluoroquinolones are antibiotics with a potential clinical side effect of phototoxicity and some are suspected to enhance UVA-induced tumorigenesis. The present study was designed to evaluate the recombinogenic and mutagenic potential of two highly photoreactive compounds, lomefloxacin and BAYy3118 when exposed to complete UVA (320-400 nm). In order to possibly increase the sensitivity of the test, we used a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-Infective Agents
Share to Diploidy
Share to DNA, Superhelical

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Dose-Response Relationship, Radiation

Share to Fluoroquinolones

Share to Mutagenicity Tests

Share to Photosensitizing Agents

Share to Quinolones

Source

Identifiers

PMID: 10863152
DOI: 10.1016/s1383-5718(00)00034-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Differences in the photogenotoxic potential of two fluoroquinolones as shown in diploid yeast strain (Saccharomyces cerevisae) and supercoiled plasmid DNA.PMID 10863152Read ↗

Photobiological effects in Saccharomyces cerevisiae induced by the monofunctional furocoumarin 4,4',6-trimethylangelicin (TMA) and the bifunctional furocoumarin 8-methoxypsoralen (8-MOP).Semantic proximity Read ↗

The photomutagenicity of fluoroquinolones in tests for gene mutation, chromosomal aberration, gene conversion and DNA breakage (Comet assay).Semantic proximity Read ↗

Lethal and mutagenic effects photoinduced in haploid yeast (Saccharomyces cerevisiae) by two new monofunctional pyridopsoralens compared to 3-carbethoxypsoralen and 8-methoxypsoralen.Semantic proximity Read ↗

Enzymatic recognition of DNA damage induced by UVB-photosensitized titanium dioxide and biological consequences in Saccharomyces cerevisiae: evidence for oxidatively DNA damage generation.Semantic proximity Read ↗

Genotoxicity of 15-deoxygoyazensolide in bacteria and yeast.Semantic proximity Read ↗

Photobiological activities of 1,6-dioxapyrene in pro- and eukaryotic cells.Semantic proximity Read ↗

Single strand breaks and mutagenesis in yeast induced by photodynamic treatment with chloroaluminum phthalocyanine.Semantic proximity Read ↗

Photomutagenicity of thiabendazole, a postharvest fungicide, in bacterial assays.Semantic proximity Read ↗

The genotoxic effects of DNA lesions induced by artificial UV-radiation and sunlight.Semantic proximity Read ↗

Toxicity, mutagenicity and transport in Saccharomyces cerevisiae of three popular DNA intercalating fluorescent dyes.Semantic proximity Read ↗

Mutational spectra induced by flavonoid extracts from pepper tree (Schinus terebinthifolius, Raddi) stem bark.Semantic proximity Read ↗

Titanium dioxide-montmorillonite nanocomposite as photoprotective agent against ultraviolet B radiation-induced mutagenesis in Saccharomyces cerevisiae: a potential candidate for safer sunscreens.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.