Article
The Herp protein pathway is not involved in the pro-amyloidogenic effect of hyperhomocysteinemia.
Journal of Alzheimer's disease : JAD - 1 Jan 2010
Zhuo Jia-Min, Kruger Warren D, Praticò Domenico
Abstract excerpt
Diet-induced high circulating levels of homocysteine, also known as hyper-homocysteinemia (HHcy), is associated with an acceleration of Alzheimer's disease-like amyloidosis. Herp is a homocysteine-responsive stress protein, which has been shown to increase the formation of amyloid-beta (Abeta) vi...
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