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Article

An intrinsic gut leptin-melanocortin pathway modulates intestinal microsomal triglyceride transfer protein and lipid absorption.

Journal of lipid research - 1 Jul 2010

Iqbal Jahangir, Li Xiaosong, Chang Benny Hung-Junn, Chan Lawrence, Schwartz Gary J, Chua Streamson C, Hussain M Mahmood

Abstract excerpt

Fat is delivered to tissues by apoB-containing lipoproteins synthesized in the liver and intestine with the help of an intracellular chaperone, microsomal triglyceride transfer protein (MTP). Leptin, a hormone secreted by adipose tissue, acts in the brain and on peripheral tissues to regulate fat...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20164094
DOI: 10.1194/jlr.M005744
PMCID: PMC2882750

Genes

LEPR
AGRP
POMC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20164094-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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