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Article

Small Intestinal Tuft Cell Activity Associates With Energy Metabolism in Diet-Induced Obesity.

Frontiers in immunology - 1 Jan 2021

Arora Pankaj, Andersen Daniel, Moll Janne Marie, Danneskiold-Samsøe Niels Banhos, Xu Liqin, Zhou Biaofeng, Kladis Georgios, Rausch Philipp, Workman Christopher T, Kristiansen Karsten, Brix Susanne

Abstract excerpt

Little is known about the involvement of type 2 immune response-promoting intestinal tuft cells in metabolic regulation. We here examined the temporal changes in small intestinal tuft cell number and activity in response to high-fat diet-induced obesity in mice and investigated the relation to whole-body energy metabolism and the immune phenotype of the small intestine and epididymal white adipose tissue. Intake...

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Identifiers

PMID: 34122403
DOI: 10.3389/fimmu.2021.629391
PMCID: PMC8195285

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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