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Article

Strong expression of IGF1R in pediatric gastrointestinal stromal tumors without IGF1R genomic amplification.

International journal of cancer - 1 Dec 2010

Janeway Katherine A, Zhu Mei-Jun, Barretina Jordi, Perez-Atayde Antonio, Demetri George D, Fletcher Jonathan A

Abstract excerpt

Wildtype (WT) gastrointestinal stromal tumors (GISTs), lacking mutations in KIT or PDGFRA, represent 85% of GISTs in pediatric patients. Treatment options for pediatric WT GIST are limited. Recently, expression profiling of a limited number of pediatric and adult WT GISTs and more in depth study...

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Source

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Identifiers

PMID: 20162573
DOI: 10.1002/ijc.25247
PMCID: PMC2947557

Genes

KIT
PDGFRA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20162573-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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