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Article

Molecular characterization of pediatric gastrointestinal stromal tumors.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 May 2008

Agaram Narasimhan P, Laquaglia Michael P, Ustun Berrin, Guo Tianhua, Wong Grace C, Socci Nicholas D, Maki Robert G, DeMatteo Ronald P, Besmer Peter, Antonescu Cristina R

Abstract excerpt

PURPOSE: Pediatric gastrointestinal stromal tumors (GIST) are rare and occur preferentially in females as multifocal gastric tumors, typically lacking mutations in KIT and PDGFRA. As KIT oncoprotein is consistently overexpressed in pediatric GIST, we sought to investigate the activation of KIT do...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18483389
DOI: 10.1158/1078-0432.CCR-07-1984
PMCID: PMC3805121

Genes

KIT
PDGFRA
BAALC
FGF4
NELL1
PLAG1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18483389-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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