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Article

Engineering clostridium strain to accept unmethylated DNA.

PloS one - 9 Feb 2010

Dong Hongjun, Zhang Yanping, Dai Zongjie, Li Yin

Abstract excerpt

It is difficult to genetically manipulate the medically and biotechnologically important genus Clostridium due to the existence of the restriction and modification (RM) systems. We identified and engineered the RM system of a model clostridial species, C. acetobutylicum, with the aim to allow the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20161730
DOI: 10.1371/journal.pone.0009038
PMCID: PMC2817722

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20161730-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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