Article
Variation at 8q24 and 9p24 and risk of epithelial ovarian cancer.
Twin research and human genetics : the official journal of the International Society for Twin Studies - 1 Feb 2010
White Kristin L, Sellers Thomas A, Fridley Brooke L, Vierkant Robert A, Phelan Catherine M, Tsai Ya-Yu, Kalli Kimberly R, Berchuck Andrew, Iversen Edwin S, Hartmann Lynn C, Liebow Mark, Armasu Sebastian, Fredericksen Zachary, Larson Melissa C, Duggan David, Couch Fergus J, Schildkraut Joellen M, Cunningham Julie M, Goode Ellen L
Abstract excerpt
The chromosome 8q24 region (specifically, 8q24.21.a) is known to harbor variants associated with risk of breast, colorectal, prostate, and bladder cancers. In 2008, variants rs10505477 and rs6983267 in this region were associated with increased risk of invasive ovarian cancer (p < 0.01); however,...
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