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Article

Phenotype and functional activity of tumor-infiltrating lymphocytes isolated from immunogenic and nonimmunogenic rat brain tumors.

Cancer research - 1 May 1991

Tzeng J J, Barth R F, Orosz C G, James S M

Abstract excerpt

The purpose of the present study was to define the immunogenicity of two transplantable rat gliomas, designated F98 and D74, and to relate this to the phenotype and functional activity of tumor-infiltrating lymphocytes (TIL). Fischer rats, immunized with irradiated F98 tumor cells and challenged with intracerebral implants of ten F98 cells, had a median survival time of 49 days compared to 36 days for...

Topics

Animals
Brain Neoplasms
Cell Separation
Cross Reactions
Glioma
Immunity, Cellular
Lymphocyte Subsets
Lymphocytes, Tumor-Infiltrating
Male
Phenotype
Rats
Rats, Inbred F344

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PMID: 2015600

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2015600-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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