Article
NOD2 status and human ileal gene expression.
Inflammatory bowel diseases - 1 Oct 2010
Hamm Christina M, Reimers Melissa A, McCullough Casey K, Gorbe Elizabeth B, Lu Jianyun, Gu C Charles, Li Ellen, Dieckgraefe Brian K, Gong Qingqing, Stappenbeck Thaddeus S, Stone Christian D, Dietz David W, Hunt Steven R
Abstract excerpt
BACKGROUND: NOD2 single nucleotide polymorphisms have been associated with increased risk of ileal Crohn's disease (CD). This exploratory study was conducted to compare ileal mucosal gene expression in CD patients with and without NOD2 risk alleles. METHODS: Ileal samples were prospectively colle...
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