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Article

Variations in critical morphine biosynthesis genes and their potential to influence human health.

Neuro endocrinology letters - 1 Jan 2010

Mantione Kirk, Kream Richard M, Stefano George B

Abstract excerpt

Endogenous morphine has been detected in human tissues from the vascular, immune and nervous systems. The genes/enzymes (CYP2D6, COMT and PNMT) that are involved in the biosynthesis of morphine have variations that affect their functionality. Some of these variations are the result of single nucl...

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Source

Identifiers

PMID: 20150871

Genes

COMT
PNMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20150871-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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